Temperature distribution studies are applied in various GMP areas as well as in different guidelines and standards. They are conducted wherever temperature is critical to process quality and ultimately the quality of the end product. This includes sterilization processes, cooling and freezing systems, storage rooms, stability chambers, and transport containers within the cold chain. For example, in a steam autoclave, the so-called cold spot and hot spot are determined, while temperature mapping in a storage room supports, among other things, the placement of fixed monitoring sensors.