Product Quality Review (PQR) is a legally required, periodic assessment that ensures pharmaceutical products are consistently manufactured and controlled according to cGMP requirements for quality, safety, and efficacy standards. In addition to retrospective analysis, the PQR also serves real-time process control and continuous improvement by providing a comprehensive view of all relevant data. By applying statistical tools, deviations are predicted and trends are identified, allowing for corrective and preventive actions to be taken if necessary. The frequency of conducting the review is based, among other factors, on historical review results but should be conducted at least once annually.